Grover disease - Doença De Grover
Doença de Grover (Grover disease) é uma condição que se apresenta repentinamente como manchas vermelhas pruriginosas no tronco, geralmente em homens idosos.
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ReferencesGrover disease, também conhecida como dermatose acantolítica transitória, é uma erupção cutânea que aparece como pápulas cheias de líquido na parte superior do tronco, principalmente em homens brancos mais velhos. Frequentemente causa prurido, mas tem curta duração. Existem quatro padrões diferentes de alterações histológicas na Grover disease, e ela tem sido associada a várias doenças, como neoplasias hematológicas. Pode ser difícil de diagnosticar e tratar, pois tende a apresentar remissão e exacerbação espontâneas. Como a Grover disease tem sido frequentemente associada a outras doenças dermatológicas e não dermatológicas da pele, é essencial descartar distúrbios concomitantes, incluindo malignidades hematopoiéticas.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Este relatório discute um caso raro de Grover's disease em um homem branco de 80 anos que apresentou erupção cutânea no peito nos últimos três a quatro meses. Ele tem histórico de hipertensão, hipercolesterolemia, artrite nos joelhos, refluxo gastroesofágico crônico, taquicardia, câncer de próstata prévio e síndrome das pernas inquietas. Inicialmente, desenvolveu uma erupção cutânea pruriginosa, eritematosa e papular, predominantemente na região superior do tronco. Apesar do uso de vários cremes e loções, os sintomas não melhoraram significativamente. Após consulta com um dermatologista e realização de biópsia de pele, o diagnóstico de Grover's disease foi confirmado. Foi então tratado com um creme esteroide por duas semanas.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
